N-terminus oligomerization is conserved in intracellular calcium release channels
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چکیده
منابع مشابه
N-terminus oligomerization is conserved in intracellular calcium release channels
Oligomerization of all three mammalian ryanodine receptor isoforms, a structural requirement for normal intracellular Ca2+ release channel function, is displayed by the discrete N-terminal domain which assembles into homo- and hetero-tetramers. This is demonstrated in yeast, mammalian cells and native tissue by complementary yeast two-hybrid, chemical cross-linking and co-immunoprecipitation as...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2014
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20131061